140129-99-3

Upstream product

• 181931-86-2 (5-methyl-2-phenyloxazol-4-yl)(5-nitrobenzofuran-2-yl)methanone 
• 97-51-8 5-Nitrosalicylaldehyde 
• 103788-62-1 4-bromoacetyl-5-methyl-2-phenyl-oxazole 
• 140129-97-1 alpha-(5-Methyl-2-phenyl-4-oxazolyl)-5-nitro-2-benzofuranmethanol 

Downstream Products

• 150563-61-4 3-[2-((5-methyl-2-phenyl-4-oxazolyl)methyl)benzofuran-5-yl]-2-(propylthio)-propanoic Acid 
• 140129-53-9 Ethyl 3-[2-((5-methyl-2-phenyl-4-oxazolyl)methyl)-benzofuran-5-yl]-2-(octylthio)propanoate 
• 140129-50-6 Ethyl 3-[2-((5-methyl-2-phenyl-4-oxazolyl)methyl)-benzofuran-5-yl]-2-(phenylmethylthio)propanoate 
• 140129-52-8 Ethyl 3-[2-((5-methyl-2-phenyl-4-oxazolyl)methyl)-benzofuran-5-yl]-2-(phenylthio)propanoate 
• 140129-27-7 ethyl 3-[2-((5-Methyl-2-phenyl-4-oxazolyl)-methyl)benzofuran-5-yl]-2-(propylthio)-propanoate 
• 140129-51-7 Ethyl 2-ethylthio-3-[2-((5-methyl-2-phenyl-4-oxazolyl)methyl)benzofuran-5-yl]propanoate 
• 1026916-55-1 3-[2-(5-Methyl-2-phenyl-oxazol-4-ylmethyl)-benzofuran-5-yl]-2-methylsulfanyl-propionic acid ethyl ester 
• 140157-69-3 ethyl alpha-bromo-2-(5-methyl-2-phenyl-4-oxazolyl)methyl-5-benzofuranpropanoic acid 
• 140129-98-2 5-Amino-2-(5-methyl-2-phenyl-4-oxazolyl)-methylbenzofuran 

Relevant academic research and scientific papers

Hypoglycemic activity of a series of α-alkylthio and α-alkoxy carboxylic acids related to ciglitazone

The thiazolidinedione moiety of ciglitazone and its analogues can be replaced by an α-alkoxy or α-thioether carboxylic acid group. The influence of the nature of the R group, the length of the connector to the aromatic backbone of the molecule, and the stereochemistry have been studied. The most potent compounds have glucose-lowering activity at doses as low as 0.01 mg/kg.