150563-61-4

Basic information

• Product Name: 3-(2-((5-methyl-2-phenyloxazol-4-yl)methyl)benzofuran-5-yl)-2-(propylsulfanyl)propionic acid
• Synonyms: 3-(2-((5-methyl-2-phenyloxazol-4-yl)methyl)benzofuran-5-yl)-2-(propylsulfanyl)propionic acid
• CAS NO: 150563-61-4
• Molecular Formula: C₂₅H₂₅NO₄S
• Molecular Weight: 435.54
• Mol File: 150563-61-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 620.4°Cat760mmHg
• Flash Point: 329°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 2.98E-16mmHg at 25°C
• Refractive Index: 1.618
• PKA: 3.63±0.46(Predicted)
• CAS DataBase Reference: 3-(2-((5-methyl-2-phenyloxazol-4-yl)methyl)benzofuran-5-yl)-2-(propylsulfanyl)propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-((5-methyl-2-phenyloxazol-4-yl)methyl)benzofuran-5-yl)-2-(propylsulfanyl)propionic acid(150563-61-4)
• EPA Substance Registry System: 3-(2-((5-methyl-2-phenyloxazol-4-yl)methyl)benzofuran-5-yl)-2-(propylsulfanyl)propionic acid(150563-61-4)

Safety Data

• Hazardous Substances Data: 150563-61-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C25H25NO4S/c1-3-11-31-23(25(27)28)13-17-9-10-22-19(12-17)14-20(30-22)15-21-16(2)29-24(26-21)18-7-5-4-6-8-18/h4-10,12,14,23H,3,11,13,15H2,1-2H3,(H,27,28)

Upstream product

• 140157-69-3 ethyl alpha-bromo-2-(5-methyl-2-phenyl-4-oxazolyl)methyl-5-benzofuranpropanoic acid 
• 140129-97-1 alpha-(5-Methyl-2-phenyl-4-oxazolyl)-5-nitro-2-benzofuranmethanol 
• 181931-86-2 (5-methyl-2-phenyloxazol-4-yl)(5-nitrobenzofuran-2-yl)methanone 
• 140129-99-3 5-Methyl-4-(5-nitro-benzofuran-2-ylmethyl)-2-phenyl-oxazole 
• 140129-98-2 5-Amino-2-(5-methyl-2-phenyl-4-oxazolyl)-methylbenzofuran 
• 97-51-8 5-Nitrosalicylaldehyde 
• 103788-62-1 4-bromoacetyl-5-methyl-2-phenyl-oxazole 
• 140129-27-7 ethyl 3-[2-((5-Methyl-2-phenyl-4-oxazolyl)-methyl)benzofuran-5-yl]-2-(propylthio)-propanoate 

Relevant articles and documents

Hypoglycemic activity of a series of α-alkylthio and α-alkoxy carboxylic acids related to ciglitazone

The thiazolidinedione moiety of ciglitazone and its analogues can be replaced by an α-alkoxy or α-thioether carboxylic acid group. The influence of the nature of the R group, the length of the connector to the aromatic backbone of the molecule, and the stereochemistry have been studied. The most potent compounds have glucose-lowering activity at doses as low as 0.01 mg/kg.

3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents

Certain 3-(phenyl, chroman-2-yl, benzofuran-5-yl, or benzoxazol-5-yl)-2-(hydroxy or mercapto)propionic acid derivatives and analogs are useful as hypoglycemic and hypocholesterolemic agents.