1401344-83-9Relevant academic research and scientific papers
Aryl-linked imidazolidin-2-ones as non-peptidic β-strand mimetics
Sutherell, Charlotte L.,Thompson, Sam,Scott, Richard T. W.,Hamilton, Andrew D.
, p. 9834 - 9836 (2012/11/13)
We describe the design and synthesis of a non-peptidic β-strand mimetic composed of alternating aryl and imidazolidin-2-one rings that can be adapted to display diverse side-chains. Solid- and solution-phase data together with calculations suggest that the desired conformation for side-chain mimicry is readily accessible and well-populated. The Royal Society of Chemistry 2012.
