1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea

Base Information

Chemical Name:1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea
CAS No.:1401344-83-9
Molecular Formula:C₄₂H₅₁N₇O₆Si
Molecular Weight:777.996
Hs Code.:

1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea

Synonyms:1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea

Suppliers and Price of 1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea

There total 12 articles about 1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1401344-82-8
(S)-3-(3-isocyanatophenyl)-4-methyl-1-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)imidazolidin-2-one

: 1401344-71-5
N-(1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-nitroaniline

: 1401344-83-9
1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea

Guidance literature:: With dmap; In dichloromethane; at 20 ℃; for 48h; Inert atmosphere;
DOI:10.1039/c2cc34791a

Reference yield:

: 1401344-70-4
(S)-2-((3-nitrophenyl)amino)propan-1-ol

: 1401344-83-9
1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea

Guidance literature:: Multi-step reaction with 12 steps

1: dmap; 1H-imidazole / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2: dmap / dichloromethane / 48 h / 20 °C

3: tetrabutyl ammonium fluoride; acetic acid / 20 °C / Inert atmosphere

4: di-isopropyl azodicarboxylate; triphenylphosphine; urea / tetrahydrofuran / 0.5 h / 20 °C

5: 5% Pd/C / ethanol / Inert atmosphere

6: sodium hydrogencarbonate / dichloromethane; water / Inert atmosphere

7: dmap / dichloromethane / 48 h / 20 °C / Inert atmosphere

8: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 20 °C

9: di-isopropyl azodicarboxylate; triphenylphosphine; urea / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere

10: acetic acid; 5% Pd/C / ethanol; toluene / 3 h / Inert atmosphere

11: sodium hydrogencarbonate / dichloromethane; water / Inert atmosphere

12: dmap / dichloromethane / 48 h / 20 °C / Inert atmosphere

With 1H-imidazole; dmap; di-isopropyl azodicarboxylate; 5% Pd/C; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; acetic acid; triphenylphosphine; urea; In tetrahydrofuran; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;
DOI:10.1039/c2cc34791a

Reference yield:

: 645-00-1
m-iodonitrobenzene

: 1401344-83-9
1-((S)-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)-3-(3-((S)-5-methyl-3-(3-((S)-5-methyl-2-oxo-3-phenylimidazolidin-1-yl)phenyl)-2-oxoimidazolidin-1-yl)phenyl)-1-(3-nitrophenyl)urea

Guidance literature:: Multi-step reaction with 13 steps

1: copper(l) iodide; potassium carbonate; L-proline / dimethyl sulfoxide / 36 h / 80 °C / Inert atmosphere

2: dmap; 1H-imidazole / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

3: dmap / dichloromethane / 48 h / 20 °C

4: tetrabutyl ammonium fluoride; acetic acid / 20 °C / Inert atmosphere

5: di-isopropyl azodicarboxylate; triphenylphosphine; urea / tetrahydrofuran / 0.5 h / 20 °C

6: 5% Pd/C / ethanol / Inert atmosphere

7: sodium hydrogencarbonate / dichloromethane; water / Inert atmosphere

8: dmap / dichloromethane / 48 h / 20 °C / Inert atmosphere

9: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 20 °C

10: di-isopropyl azodicarboxylate; triphenylphosphine; urea / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere

11: acetic acid; 5% Pd/C / ethanol; toluene / 3 h / Inert atmosphere

12: sodium hydrogencarbonate / dichloromethane; water / Inert atmosphere

13: dmap / dichloromethane / 48 h / 20 °C / Inert atmosphere

With 1H-imidazole; dmap; copper(l) iodide; di-isopropyl azodicarboxylate; 5% Pd/C; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; potassium carbonate; acetic acid; triphenylphosphine; urea; L-proline; In tetrahydrofuran; ethanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene;
DOI:10.1039/c2cc34791a