140137-89-9

Basic information

• Product Name: Benzene, [(chlorofluoromethyl)sulfinyl]-
• CAS NO: 140137-89-9
• Molecular Formula: C7H6ClFOS
• Molecular Weight: 192.641
• Mol File: 140137-89-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, [(chlorofluoromethyl)sulfinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(chlorofluoromethyl)sulfinyl]-(140137-89-9)
• EPA Substance Registry System: Benzene, [(chlorofluoromethyl)sulfinyl]-(140137-89-9)

Safety Data

• Hazardous Substances Data: 140137-89-9(Hazardous Substances Data)

Upstream product

• 108-98-5 thiophenol 
• 130755-47-4 (dichlorofluoromethyl)(phenyl)sulfide 
• 882-33-7 diphenyldisulfane 
• 116109-54-7 chlorofluoromethyl phenyl sulfide 

Downstream Products

• 14213-84-4 2-phenylethylstyrene 
• 5407-91-0 1,4-diphenylbutan-1-one 
• 20405-78-1 (Z)-(2-fluorovinyl)benzene 
• 123133-09-5 2-(4-biphenylyl)-1-chloro-1-fluoroethyl phenyl sulfoxide 
• 123133-10-8 1-chloro-1-fluoro-2-(1-naphthyl)ethyl phenyl sulfoxide 
• 123133-12-0 1-chloro-1-fluoro-4-phenylbutyl phenyl sulfoxide 
• 123133-11-9 1-chloro-1-fluoro-2-phenylethyl phenyl sulfoxide 
• 140137-79-7 (S*_S,1S*,2S*)-2-(4-biphenylyl)-1-chloro-1-fluoro-2-hydroxyethyl phenyl s 
• 140137-79-7 (S*_S,1R*,2R*)-2-(4-biphenylyl)-1-chloro-1-fluoro-2-hydroxyethyl phenyl s 
• 140137-79-7 (S*_S,1S*,2R*)-2-(4-biphenylyl)-1-chloro-1-fluoro-2-hydroxyethyl phenyl sulfoxide 
• 140137-79-7 (S*_S,1R*,2S*)-2-(4-biphenylyl)-1-chloro-1-fluoro-2-hydroxyethyl phenyl s 
• 140137-80-0 (S*_S,1R*,2S*)-1-chloro-1-fluoro-2-hydroxy-4-phenylbutyl phenyl sulfoxide 
• 140137-80-0 (S*_S,1R*,2R*)-1-chloro-1-fluoro-2-hydroxy-4-phenylbutyl phenyl sulfoxide 
• 140137-80-0 (S*_S,1S*,2R*)-1-chloro-1-fluoro-2-hydroxy-4-phenylbutyl phenyl sulfoxide 

Relevant articles and documents

Difluoromethyl and chlorofluoromethyl sulfoximines: Synthesis and evaluation as electrophilic perfluoroalkylating reagents

An efficient and convenient method is described that allows the synthesis of a set of difluoromethyl sulfoximines, as well as chlorofluoromethyl sulfoxides, sulfones, and sulfoximines. Our procedure does not require metals or nonrecommended freons, and it gives rise to an original route to Hu's reagent. Unprecedented chlorofluoromethyl sulfoximines have been also isolated, and these compounds have been shown to act as an electrophilic source of this original bis-halogenated moiety. The mechanism of the electrophilic chlorofluoromethylation is also discussed. Bromodifluoromethyl and dichlorofluoromethyl sulfoximines are transformed into the Hu electrophilic difluoromethylating reagent, and into a new chlorofluoromethylating reagent, respectively.

Behaviors of α-Fluorocarbenoids Derived from the Nucleophilic Desulfinylation of α-Chloro-α-fluoroalkyl Sulfoxides

2-Aryl-1-chloro-1-fluoroethyl sulfoxides underwent nucleophilic desulfinylation with PhMgBr to give (Z)-fluorostyrene derivatives in a very stereoselective manner (>33:1) via an α-fluorocarbene species.When treated with 3 equiv of PhLi in the presence of N,N,N',N'-tetramethylethylenediamine, they similarly formed fluorostyrenes as a stereoisomeric mixture (E:Z = 2:1), but with 1 equiv of PhLi 1-aryl-1-chloro-1-fluoroethanes were the major product.On the other hand, no formation of a fluoroalkene was observed in the desulfinylation of 1-chloro-1-fluoro-4-phenylbutyl sul foxide with the nucleophiles.In the latter reaction, oxidation and/or phenylation of the intermediate carbene were the main pathways.