140145-71-7

Upstream product

• 110-52-1 1,4-dibromo-butane 
• 1795-98-8 rac-phenylalaninol 
• 123-75-1 pyrrolidine 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 

Downstream Products

• 140145-72-8 1-(1-Benzyl-2-chlorethyl)-pyrrolidin 
• 139925-18-1 1-(1-Benzyl-4-hydroxybutyl)-pyrrolidin 
• 139925-27-2 5-Phenyl-4-pyrrolidinyl-valeriansaeureethylester 
• 139925-17-0 1-(1-Benzyl-4-hydroxybutyl)-pyrrolidin-2-on 
• 139925-26-1 2-(3-Phenyl-2-pyrrolidin-1-yl-propyl)-malonsaeurediethylester 

Relevant academic research and scientific papers

Hydroamination of cinnamyl alcohol using lithium amides

Hydroamination of cinnamyl alcohol is possible by reaction with lithium amides derived from primary or cyclic secondary amines.

Synthesis of possible metabolites and the enantiomers of prolintane

The synthesis of 15 possible metabolites of prolintane (1) (Katovit) which is used in the treatment of blood pressure disregualtions is described. Furthermore, the preparation of the enantiomers of 1 is reported, starting with R-(+)- and S-(-)-phenylalaninol respectively.