1401669-95-1Relevant academic research and scientific papers
PEG-mediated catalyst-free expeditious synthesis of polysubstituted anilines and benzenes via the reaction of malononitrile and β-ketoester derivatives in the presence of activated acetylenes
Piltan, Mohammad,Moradi, Loghman,Salimi, Hiwa,Zargoosh, Kiomars,Zarei, Seyed Amir
, p. 571 - 575 (2012)
Poly(ethylene glycol) (PEG) has been used as a sustainable, non-volatile, and environmentally friendly reaction solvent for synthesis of functionalized anilines and benzenes via the reaction of malononitrile and β-ketoester derivatives in the presence of activated acetylenes at 80o C. No additional solvent and catalyst are required.
