1401693-29-5Relevant articles and documents
Synthesis of 3,4-dihalogenated furan-2-(5H)-ones by electrophilic cyclization of 4-hydroxy-2-alkynoates
Zhu, Hai-Tao,Wang, Li-Jing,Ji, Ke-Gong,Liu, Xue-Yuan,Liang, Yong-Min
, p. 1862 - 1866 (2012/09/07)
Functionalized 3,4-dihalogenated furan-2(5H)-ones can be readily prepared in moderate to good yields by treating 4-hydroxy-4-arylbut-2-ynoate derivatives with ICl, IBr, and I2. Both halogen atoms of the electrophile are incorporated in the product. The resulting halides can further afford polycyclic aromatic compounds using known palladium-catalyzed coupling reactions.