1401710-48-2Relevant academic research and scientific papers
A new synthetic approach to phenothiazine-2-amines
Takács, Daniella,Egyed, Orsolya,Drahos, László,Riedl, Zsuzsanna,Hajós, Gy?rgy
, p. 5585 - 5588 (2012/10/29)
Elaboration of a Buchwald-Hartwig protocol for the introduction of amino functions to position 2 of the phenothiazine ring system has opened a new access to various N-alkyl and N-dienyl phenothiazines bearing secondary amines, tertiary amines, and amide moieties. Hydrolysis of the amido derivatives gave unsubstituted phenothiazine-2-amines. This protocol provides an easy access to phenothiazine-2-amines starting from the commercially available starting compounds.
