1401714-41-7Relevant academic research and scientific papers
Determination of rate constants for trifluoromethyl radical addition to various alkenes via a practical method
Hartmann,Li,Studer
, p. 206 - 210 (2015)
A simple and practical method for the determination of rate constants for trifluoromethyl radical addition to various alkenes by applying competition kinetics is introduced. In the kinetic experiments the trifluoromethyl radicals are generated in situ from a commercially available hypervalent-iodine-CF3 reagent (Togni-reagent) by SET-reduction with TEMPONa in the presence of TEMPO and a π-acceptor. From the relative ratio of TEMPOCF3 and CF3-addition product formed, which is readily determined by 19F-NMR spectroscopy, rate constants for trifluoromethyl radical addition to the π-acceptor can be calculated. The practical method is also applicable to measure rate constants for the addition of other perfluoroalkyl radicals to alkenes as documented for CF3CF2-radical addition reactions.
Transition-metal-free trifluoromethylaminoxylation of alkenes
Li, Yi,Studer, Armido
supporting information; experimental part, p. 8221 - 8224 (2012/09/07)
No transition metal! Fluorinated hypervalent-iodine reagents react with TEMPONa in the presence of an alkene under mild conditions to give the corresponding perfluoroalkylaminoxylation products. These radical addition/trapping reactions occur with high st
