140176-58-5Relevant articles and documents
Asymmetric Synthesis of Oxygen- and Nitrogen-Substituted Difluoromethylene Products
Bravo, Pierfrancesco,Pregnolato, Massimo,Resnati, Giuseppe
, p. 2726 - 2731 (2007/10/02)
1,1-Difluoroalkyl sulfinylmethyl ketones 3 are synthesized in enantiomerically pure form through acylation of (+)-(R)-methyl p-tolyl sulfoxide (1) with α,α-difluorocarboxylates 2.These ketones have been reduced with complete diastereoselection to give the