140176-89-2

Upstream product

• 100-65-2 N-Phenylhydroxylamine 
• 140176-83-6 benzyl (+/-)-2-phenyl-3-oxo-5-isoxazolidinecarboxylate 
• 140176-81-4 (+/-)-2-phenyl-5-(hydroxymethyl)isoxazolidin-3-one 
• 141-75-3 butyryl chloride 

Downstream Products

• 140384-99-2 (R)-(-)-2-phenyl-5-<(dimethylamino)methyl>isoxazolidin-3-one methiodide 
• 140385-00-8 (S)-(+)-2-phenyl-5-<(dimethylamino)methyl>isoxazolidin-3-one methiodide 
• 140176-85-8 (R)-(-)-2-phenyl-5-<(dimethylamino)methyl>isoxazolidin-3-one 
• 140385-01-9 (S)-(+)-2-phenyl-5-<(dimethylamino)methyl>isoxazolidin-3-one 
• 140384-90-3 (R)-5-Hydroxymethyl-2-phenyl-isoxazolidin-3-one 
• 140384-94-7 Butyric acid (R)-3-oxo-2-phenyl-isoxazolidin-5-ylmethyl ester 
• 140384-89-0 (S)-5-Hydroxymethyl-2-phenyl-isoxazolidin-3-one 
• 140384-93-6 Butyric acid (S)-3-oxo-2-phenyl-isoxazolidin-5-ylmethyl ester 

Relevant academic research and scientific papers

Nitrile Oxides in Medicinal Chemistry. 4. Chemoenzymatic Synthesis of Chiral Heterocyclic Derivatives

The two enantiomers of 3-bromo-5-(hydroxymethyl)-Δ2-isoxazoline (1) and 2-phenyl-5-(hydroxymethyl)-isoxazolidin-3-one (9) have been prepared in enantiomeric excess higher than 90percent by hydrolysis of the corresponding butyrates under the cat