1401797-64-5Relevant academic research and scientific papers
Scope and limitation for FeSO4-mediated direct arylation of heteroarenes with arylboronic acids and its synthetic applications
Komeyama, Kimihiro,Nagao, Yuya,Abe, Manabu,Takaki, Ken
, p. 301 - 313 (2014/03/21)
FeSO4-mediated direct arylation of heteroarenes with arylboronic acids in the presence of K2S2O8 has been developed. A slow addition of an aqueous solution of an iron complex was crucial in the arylation. Scope and limitation of the heteroarenes and arylboronic acids are discussed. Furthermore, the direct arylation was applied to the formal total synthesis botryllazine B and sodium channel inhibitor.
[4+2] Annulation of vinyl ketones initiated by a phosphine-catalyzed aza-Rauhut-currier reaction: A practical access to densely functionalized tetrahydropyridines
Shi, Zugui,Tong, Qinjie,Leong, Wendy Wen Yi,Zhong, Guofu
, p. 9802 - 9806 (2012/09/07)
The first example of phosphine catalyzed aza-Rauhut-Currier reaction initiated [4+2] annulation of vinyl ketones with N-sulfonyl-1-aza-1,3-dienes has been disclosed. Under the ambient conditions, this protocol provides a practical access to valuable densely functionalized tetrahydropyridines in good to excellent yields and high diastereoselectivities (see scheme). Copyright
