1401966-71-9

Upstream product

• 1401966-70-8 tert-butyl 4-((4-(hydroxymethyl)piperidin-1-yl)methyl)benzoate 
• 6457-49-4 4-piperidinemethanol 
• 108052-76-2 4-(bromomethyl)benzoic acid 1,1-dimethylethyl ester 

Relevant academic research and scientific papers

Cyclopropylamines as LSD1 inhibitors

This invention relates to the use of cyclopropylamine derivatives for the modulation, notably the inhibition of the activity of Lysine-specific demethylase 1 (LSD1). Suitably, the present invention relates to the use of cyclopropylamines in the treatment of cancer.

THERAPEUTIC COMPOUNDS AND USES THEREOF

Provided herein are compounds of formula I: and salts thereof and compositions and uses thereof. The compounds are useful as inhibitors of LSD1. Also included are pharmaceutical compositions comprising a compound of formula I or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various LSD1-mediated disorders.

LSD1 Fluorocyclopropylamine as inhibitor

This invention relates to the use of cyclopropylamine derivatives for the modulation, notably the inhibition of the activity of Lysine-specific demethylase 1 (LSD1). Suitably, the present invention relates to the use of cyclopropylamines in the treatment of cancer.