140202-30-8

Upstream product

• 108540-72-3 4-bromophenylalanine-hydrochloride 
• 79-22-1 methyl chloroformate 
• 14091-15-7 p-bromo-DL-phenylalanine 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 71078-92-7 diethyl (acetylamino)<(4-bromophenyl)methyl>propanedioate 

Downstream Products

• 140202-31-9 methyl 4-bromo-N-(methoxycarbonyl)phenylalaninate 

Relevant academic research and scientific papers

Generation of N-Methyl-D-aspartate Agonist and Competitive Antagonist Pharmacophore Models. Design and Synthesis of Phosphonoalkyl-Substituted Tetrahydroisoquinolines as Novel Antagonists

The preparation and binding affinity of a series of tetrahydroisoquinoline carboxylic acids at the N-methyl-D-aspartate (NMDA) subtype of the glutamate receptor is described, together with a molecular modeling analysis of NMDA agonists and antagonists.Usi

Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity

The invention includes a novel series of substituted aryl or heteroaryl fused 2- or 6-carboxy piperidines and derivatives thereof which are useful in the treatment of cerebrovascular disorders, epilepsy, Huntington's disease, or as anesthetics particularly in surgical processes where a finite risk of cerebrovascular damage exists. Processes for making the compounds, novel intermediates useful in the processes, methods for using, and compositions containing the compounds are also included.