1402133-13-4Relevant academic research and scientific papers
Synthesis of (E)-iodo vinylsulfones via oxidative addition of thiol into alkyne under metal free condition
Samanta, Surya Kanta,Sarkar, Rumpa,Bera, Mrinal K.
, (2021)
An efficient, transition-metal free and molecular iodine promoted protocol for the construction of (E)-β-iodovinyl sulfone derivatives via oxidative C–S coupling of thiol and alkyne has been demonstrated. Both aryl and alkyl terminal acetylenes were found to be an excellent substrate for the present reaction which provides a wide range of β-iodovinyl sulfone derivatives with very good yield and excellent regio and stereo-selectivities. Diaryldisulfide is also found to be an equally efficient sulfonyl group surrogate under identical reaction conditions.
Direct difunctionalization of alkynes with sulfinic acids and molecular iodine: A simple and convenient approach to (E)-β-iodovinyl sulfones
Wei, Wei,Wen, Jiangwei,Yang, Daoshan,Jing, Huijun,You, Jinmao,Wang, Hua
, p. 4416 - 4419 (2015/02/19)
A simple and convenient approach for the construction of β-iodovinyl sulfones has been developed via direct difunctionalization of alkynes with sulfinic acids and molecular iodine. The present reaction provides a highly efficient approach to a diverse range of substituted (E)-β-iodovinyl sulfones in moderate to good yields with excellent stereo- and regio-selectivities but no need for any metal catalyst or additives.
