1402231-80-4Relevant academic research and scientific papers
Highly stereoselective synthesis of tertiary propargylic centers and their isomerization to enantiomerically enriched allenes
García Ruano, José Luis,Marzo, Leyre,Marcos, Vanesa,Alvarado, Cuauhtémoc,Alemán, José
, p. 9775 - 9779 (2012)
Center of attention: A new approach for the synthesis of enantiomerically enriched allenes by isomerization of 2-p-tolylsulfinylphenyl propargylic derivatives is presented, which in turn are prepared by reaction of sulfinylated lithium benzylcarbanions with arylsulfonylacetylenes (see scheme). The high control of stereoselectivity in both steps is exerted by the sulfinyl group. Copyright
Synthesis of enantiopure 1,5-enynes and 1,5-diynes with propargylic quaternary centers
Pérez, Ignacio,Yuste, Francisco,Sánchez-Obreg?n, Rubén,Toscano, Rubén A.,Alemán, José,Marzo, Leyre,Martín Castro, Ana M.,Alonso, Inés,García Ruano, José Luis
, p. 3314 - 3319 (2015)
Diastereoselective quaternization of ortho-sulfinylbenzyl-methylpropargylic carbanions has been carried out with various allylic, propargylic, and benzylic halides. The stereoselectivity is efficiently controlled by the sulfinyl group, acting as a remote
Stereocontrolled Addition of Scrambling ortho-Sulfinyl Carbanions: Easy Access to Homopropargylamines and α-Allenylamines
Alemán, José,Cruz-Delgado, Balú,Rodríguez, Ricardo I.,Rosado-Abón, Anielka,Sánchez-Obregón, Rubén,Yuste, Francisco
supporting information, (2020/03/26)
An unprecedented behavior of ortho-sulfinylpropargyl carbanions in the presence of optically active sulfinylimines affords two different families of compounds: This peculiar chemodivergency is importantly affected by the nature of the employed base, and a
