140225-27-0

Upstream product

• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 146557-69-9 1-[5-(tert-butyldiphenylsilyl)-2,3-dideoxy-3-C-(formyl)-β-D-erythro-pentofuranosyl]thymine 
• 140209-48-9 1-[(4R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-vinyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 140209-46-7 Acetic acid (4R,5S)-5-(tert-butyl-diphenyl-silanyloxymethyl)-4-vinyl-tetrahydro-furan-2-yl ester 
• 140209-45-6 (4R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-vinyl-dihydro-furan-2-one 
• 99315-76-1 (5S)-5-(tert-butyldiphenylsiloxymethyl)-2(5H)-furanone 

Downstream Products

• 1210349-18-0 C₅₅H₆₀N₄O₈Si₂ 
• 1210349-11-3 C₅₅H₆₄N₄O₈Si₂ 

Relevant academic research and scientific papers

Synthesis of carbon E, e -diene chain-linked dinucleotide analogues

The synthesis of a dinucleotide thymidine-thymidine linked by a carbon E,E-diene chain is described. This dimer is synthesized by a coupling reaction between an (E)-vinylstannane and an (E)-iodovinyl partner prepared from acetylenic parents, which are bot

Synthesis of 3'-ethynylthymidine, 3'-vinylthymidine and 3'-bromovinylthymidine as potential antiviral agents

The synthesis of three novel 3'-unsaturated carbon analogues of AZT and FLT is described. The key step in the synthesis is a Cu(I)-catalyzed addition of vinylmagnesium bromide to a 2,3-unsaturated lactone, followed by, in the case of compounds 2 and 3, el