140241-50-5Relevant academic research and scientific papers
Synthesis of functionalized amino acids by ring-opening reactions of aliphatically substituted aziridine-2-carboxylic esters
Legters, Johan,Willems, G. H.,Thijs, Lambertus,Zwanenburg, Binne
, p. 59 - 68 (2007/10/02)
Nucleophilic ring-opening reactions of 3-alkylaziridine-2-carboxylic esters are described.Without ring activation at nitrogen, ring opening could only be accomplished with etheral hydrogen chloride.Introduction of electron-withdrawing activating groups at
