1402604-36-7Relevant academic research and scientific papers
Aminofluorination of 2-alkynylanilines: A Au-catalyzed entry to fluorinated indoles
Arcadi, Antonio,Pietropaolo, Emanuela,Alvino, Antonello,Michelet, Veronique
, p. 449 - 458 (2014)
The scope and limitations of gold-catalyzed tandem cycloisomerization/ fluorination reactions of unprotected 2-alkynylanilines to have access to 3,3-difluoro-2-aryl-3H-indoles and 3-fluoro-2-arylindoles are described. An unprecedented aminoauration/oxidation/ fluorination cascade reaction of 2-alkynylanilines bearing a linear alkyl group on the terminal triple bond is reported.
Silver-catalyzed one-pot cyclization/fluorination of 2-alkynylanilines: Highly efficient synthesis of structurally diverse fluorinated indole derivatives
Yang, Lei,Ma, Yuanhong,Song, Feijie,You, Jingsong
supporting information, p. 3024 - 3026 (2014/03/21)
Highly efficient approaches to obtain structurally diverse fluorinated indole derivatives have been realized through the Ag-catalyzed one-pot cyclization/fluorination of 2-alkynylanilines in the presence of NFSI or Selectfluor. The Royal Society of Chemistry.
One-pot gold-catalyzed aminofluorination of unprotected 2-alkynylanilines
Arcadi, Antonio,Pietropaolo, Emanuela,Alvino, Antonello,Michelet, Véronique
supporting information, p. 2766 - 2769 (2013/07/19)
A tandem gold(I)-catalyzed aminocylization/fluorination and a two-step, one-pot gold(III)-catalyzed cyclization/electrophilic fluorination provide a convenient and general method for the synthesis of 3,3-difluoro-2-substituted- 3H-indoles in good yield un
Exploration of forbidden povarov processes as a source of unexpected reactivity: A multicomponent Mannich-Ritter transformation
Preciado, Sara,Vicente-García, Esther,Llabrés, Salomé,Luque, F. Javier,Lavilla, Rodolfo
supporting information; experimental part, p. 6874 - 6877 (2012/10/08)
When a door closes, a window opens! The use of geometrically or electronically restricted imines for Povarov-type processes does not afford the anti-Bredt tetrahydroquinolines, but leads instead to highly functionalized structures through novel reaction pathways (see picture; LA=Lewis acid). The exploration of forbidden routes constitutes a valuable approach in the search for new multicomponent reactions. Copyright
