1402671-71-9Relevant articles and documents
Synthesis of 3-alkenylated indole and bis(indol-3-yl) derivatives catalyzed by sulfonic acid-functionalized ionic liquid under ultrasound irradiation
Budania, Saroj,Shelke, Ganesh M.,Kumar, Anil
, p. 646 - 654 (2017)
A simple and efficient protocol has been developed for the synthesis of 3-alkenylated indoles and bis(indol-3-yl) derivatives by sulfonic acid-functionalized ionic liquid-catalyzed reaction of indole with 1,3-diketones/3-ketoesters under solvent-free ultrasound irradiation. Good to excellent yields (68–94%) are obtained in ultrasonication. The product of reaction is dependent on the substituent at C-2 position of indole. The catalyst is reusable and recyclable up to four cycles without significant loss of its catalytic activity. Compared with conventional heating, sound wave activation has the considerable advantages such as shorter reaction time, easy work-up, higher yields, and mild conditions.
Ionic liquid phase synthesis (IoLiPS) of 2-aminothiazoles and imidazo[1,2-a]pyridines
Choudhary, Sunita,Muthyala, Manoj Kumar,Kumar, Anil
, p. 47368 - 47372 (2014)
An efficient and practical ionic liquid phase synthesis (IoLiPS) of aza-heterocycles has been developed through a 'catch-and-release' strategy using an ionic liquid-supported hypervalent iodine reagent. The hypervalent iodine played a dual role as a reagent and as a soluble support. This strategy provided a combinatorial approach for the synthesis of 2-aminothiazoles and imidazo[1,2-a]pyridines directly from substituted acetophenones in good to excellent yields. The use of an ionic liquid supported reagent offered better isolation of the products by simple extraction with organic solvents. This journal is
Ionic liquid as soluble support for synthesis of 1,2,3-thiadiazoles and 1,2,3-selenadiazoles
Kumar, Anil,Muthyala, Manoj Kumar,Choudhary, Sunita,Tiwari, Rakesh K.,Parang, Keykavous
, p. 9391 - 9396,6 (2012/12/11)
A convenient synthesis of 1,2,3-thiadiazoles and 1,2,3-selenadiazoles was achieved using an ionic liquid as a novel soluble support. Ionic liquid-supported sulfonyl hydrazine was synthesized and reacted with a number of ketones to afford the corresponding ionic liquid-supported hydrazones that were converted to 1,2,3-thiadiazoles in the presence of thionyl chloride. The reaction of ionic liquid-supported hydrazones with selenium dioxide in acetonitrile afforded 1,2,3-selenadiazoles. The advantages of this methodology were the ease of workup, simple reaction conditions, and high purity.