1402729-33-2Relevant academic research and scientific papers
Design and synthesis of curcumin derivatives as tau and amyloid β dual aggregation inhibitors
Okuda, Michiaki,Hijikuro, Ichiro,Fujita, Yuki,Teruya, Takayuki,Kawakami, Hirochika,Takahashi, Takashi,Sugimoto, Hachiro
, p. 5024 - 5028 (2016/10/05)
Alzheimer's disease (AD) is the most common form of dementia. In an AD patient's brain, senile plaques and neurofibrillary tangles, the abnormal aggregates of amyloid β (Aβ) peptide and tau protein, are observed as the two major hallmarks of this disease.
NOVEL PYRAZOLE DERIVATIVE
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Paragraph 0138; 0289, (2014/03/22)
Provided is a novel therapeutic means for Alzheimer's disease. In particular, provided is a compound represented by the following general formula (I): [wherein Ar1 represents 2-methoxy-4-(2-pyridylmethoxy)phenyl etc. and Ar2 represents a 1H-indol-6-yl group etc.] or a salt thereof.
