1403333-89-0

Upstream product

• 3017-69-4 2-methyl-1-propenylbromide 
• 15366-34-4 methyl 1H-pyrazole 3-carboxylate 

Downstream Products

• 1403333-88-9 (S)-N-(1-(3-(3-Chloro-4-cyano-5-fluorophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1-(2-methylprop-1-enyl)-1H-pyrazole-3-carboxamide 
• 1403334-29-1 (S)-N-(1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1-(2-methylprop-1-enyl)-1H-pyrazole-3-carboxamide 

Relevant academic research and scientific papers

ANDROGEN RECEPTOR MODULATING CARBOXAMIDES

Compounds of formula (I) or (II) wherein Rx, Rz, R9, R10, R14, R14′, R15, R15′, A and B are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds possess utility as tissue-selective androgen receptor modulators (SARM) and are useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.