1403395-80-1

Basic information

• Product Name: (3-{1-[4-(1-isopropyl-1H-pyrazol-4-yl)phenyl]cyclopropyl}-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepin-8-yl)methanol
• Synonyms: (3-{1-[4-(1-isopropyl-1H-pyrazol-4-yl)phenyl]cyclopropyl}-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepin-8-yl)methanol
• CAS NO: 1403395-80-1
• Molecular Weight: 423.582
• Mol File: 1403395-80-1.mol

Chemical Properties

• CAS DataBase Reference: (3-{1-[4-(1-isopropyl-1H-pyrazol-4-yl)phenyl]cyclopropyl}-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepin-8-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3-{1-[4-(1-isopropyl-1H-pyrazol-4-yl)phenyl]cyclopropyl}-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepin-8-yl)methanol(1403395-80-1)
• EPA Substance Registry System: (3-{1-[4-(1-isopropyl-1H-pyrazol-4-yl)phenyl]cyclopropyl}-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepin-8-yl)methanol(1403395-80-1)

Safety Data

• Hazardous Substances Data: 1403395-80-1(Hazardous Substances Data)

Upstream product

• 16532-79-9 4-Bromophenylacetonitrile 
• 345965-52-8 1-(4-bromophenyl)cyclopropanecarboxylic acid 
• 1403396-86-0 8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-3-{1-[4-(1-isopropyl-1H-pyrazol-4-yl)phenyl]cyclopropyl}-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine 
• 1098360-87-2 1-(4-bromophenyl)cyclopropanecarbohydrazide 
• 1403396-19-9 tert-butyl 2-{[1-(4-bromophenyl)cyclopropyl]carbonyl}hydrazinecarboxylate 
• 1403396-20-2 3-[1-(4-bromophenyl)cyclopropyl]-8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine 

Relevant articles and documents

TETRAHYDROTHIAZEPINE DERIVATIVE

The present invention relates to a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof having an excellent effect of inhibiting 11β-hydroxysteroid dehydrogenase type 1: General formula (I) wherein R1 represents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from substituent group A or a heterocyclic group that may be substituted with 1 to 4 group(s) independently selected from substituent group A; R2 independently represents a halogen atom or a C1-C6 alkyl group; n represents an integer of 0 to 2; and substituent group A represents the group consisting of halogen atoms, C1-C6 alkyl groups, and so forth.