1403608-13-8

Basic information

• Product Name: 2-hydroxy-4-methoxy-6-vinylbenzaldehyde
• Synonyms: 2-hydroxy-4-methoxy-6-vinylbenzaldehyde
• CAS NO: 1403608-13-8
• Molecular Weight: 178.188
• Mol File: 1403608-13-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-4-methoxy-6-vinylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-4-methoxy-6-vinylbenzaldehyde(1403608-13-8)
• EPA Substance Registry System: 2-hydroxy-4-methoxy-6-vinylbenzaldehyde(1403608-13-8)

Safety Data

• Hazardous Substances Data: 1403608-13-8(Hazardous Substances Data)

Upstream product

• 40243-87-6 3,5-dimethoxystyrene 
• 2150-37-0 methyl 3,5-dimethoxybenzoate 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 91142-86-8 4,6-dimethoxy-2-vinyl-benzaldehyde 
• 705-76-0 3,5-dimethoxybenzyl alcohol 

Downstream Products

• 1403608-19-4 (S,E)-5-{(4S,5S)-5-[(S)-1-(4-methoxybenzyloxy)but-3-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}pent-4-en-2-yl 2-hydroxy-4-methoxy-6-vinylbenzoate 
• 1403608-20-7 (R,E)-5-{(4S,5S)-5-[(S)-1-hydroxybut-3-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}pent-4-en-2-yl 2-hydroxy-4-methoxy-6-vinylbenzoate 
• 66018-41-5 zeaenol 

Relevant articles and documents

Asymmetric total syntheses of cochliomycin A and zeaenol

The first asymmetric total syntheses of two resorcylic acid lactones (RALs) - cochliomycin A and zeaenol - have been achieved in a divergent way. The main highlight of our strategy involves successful application of stereoselecive Keck allylation and Julia-Kocienski olefination to access an advanced intermediate, by starting from L-tartaric acid as a chiral pool compound. This intermediate is coupled with a trisubstituted benzoic acid to afford a common RCM precursor for both target molecules. Ring-closing metathesis at a late stage, followed by functional group manipulation, yielded the target molecules in an efficient way. Two resorcylic acid lactones (RALs) - cochliomycin A and zeaenol - have been synthesized for the first time by an enantiodivergent route from the common chiral pool compound L-tartaric acid. Copyright