140367-31-3Relevant academic research and scientific papers
AMINOMETHYLATION OF N,N'- AND N,N,N'-SUBSTITUTED UREAS BY N-METHYLENE-tert-BUTYLAMINE
Kovalenko, A. L.,Serov, Yu. V.,Nikonov, A. A.,Tselinskii, I. V.
, p. 1835 - 1837 (2007/10/02)
The reaction of 1,3-substituted ureas with N-methylene-tert-butylamine in the absence of a solvent proceeds via mechanism of the Mannich type to give 1-R1-3-R2-5-tert-butyl-3,4,5,6-tetrahydro-1,3,5-triazin-2-ones and tert-butylamine. 1,1,3-Substituted ureas do not react with N-methylene-tert-butylamine as a consequence of the steric hindrance created by the tert-butyl grouping to obtaining the key iminium salt.
