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Upstream product

• 1315362-38-9 2-azido-1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 62452-73-7 1-ethynyl-4-propylbenzene 
• 60965-24-4 2-bromo-1-(2-hydroxy-4-methoxy-phenyl)-ethanone 

Relevant academic research and scientific papers

Synthesis of paeonol derivatives linked with 1,2,3-triazole moiety by 1,3-dipolar huisgen-cylcoaddition reaction

Paeonol is a major phenolic component isolated from Moutan Cortex, a traditional Chinese medicine. An efficient synthesis of paeonol derivatives linked to a 1,2,3-triazole moiety using a 1,3-dipolar Huisgen-cycloaddition reaction is described. The paeonol derivatives are regioselectively obtained in good yields under mild conditions using Cu(OAc)2·H 2O/sodium ascorbate as a catalyst system, and t-BuOH/H2O (1:1, v/v) as a co-solvent.