Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1403903-28-5

Post Buying Request

1403903-28-5 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1403903-28-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1403903-28-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,3,9,0 and 3 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1403903-28:
(9*1)+(8*4)+(7*0)+(6*3)+(5*9)+(4*0)+(3*3)+(2*2)+(1*8)=125
125 % 10 = 5
So 1403903-28-5 is a valid CAS Registry Number.

1403903-28-5Relevant articles and documents

Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP)

Tamanini, Emiliano,Buck, Ildiko M.,Chessari, Gianni,Chiarparin, Elisabetta,Day, James E. H.,Frederickson, Martyn,Griffiths-Jones, Charlotte M.,Hearn, Keisha,Heightman, Tom D.,Iqbal, Aman,Johnson, Christopher N.,Lewis, Edward J.,Martins, Vanessa,Peakman, Torren,Reader, Michael,Rich, Sharna J.,Ward, George A.,Williams, Pamela A.,Wilsher, Nicola E.

, p. 4611 - 4625 (2017/06/13)

XIAP and cIAP1 are members of the inhibitor of apoptosis protein (IAP) family and are key regulators of anti-apoptotic and pro-survival signaling pathways. Overexpression of IAPs occurs in various cancers and has been associated with tumor progression and resistance to treatment. Structure-based drug design (SBDD) guided by structural information from X-ray crystallography, computational studies, and NMR solution conformational analysis was successfully applied to a fragment-derived lead resulting in AT-IAP, a potent, orally bioavailable, dual antagonist of XIAP and cIAP1 and a structurally novel chemical probe for IAP biology.

BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY

-

, (2014/05/07)

The invention relates to new bicyclic heterocycle compounds of formula (I):,to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1403903-28-5