1403941-83-2

Upstream product

• 721450-11-9 3-chloro-1H-pyrrole-2-carbonyl chloride 
• 1403941-84-3 3-chloro-N-o-tolyl-1H-pyrrole-2-carboxamide 
• 1053658-09-5 3-chloro-1H-pyrrole-2-carboxylic acid 
• 95-53-4 o-toluidine 

Downstream Products

• 1403941-87-6 3-chloro-1-(2-chloroacetamido)-N-o-tolyl-1H-pyrrole-2-carboxamide 
• 1403941-85-4 5-chloro-2-(chloromethyl)-3-o-tolylpyrrolo[1,2-f][1,2,4]triazin-4(3H)-one 
• 1403941-88-7 2-(aminomethyl)-5-chloro-3-o-tolylpyrrolo[1,2-f][1,2,4]triazin-4(3H)-one 
• 1403945-65-2 2-((6-amino-9H-purin-9-yl)methyl)-5-chloro-3-o-tolylpyrrolo[1,2-f][1,2,4]triazin-4(3H)-one 
• 1403945-67-4 2-((6-aminopyrimidin-4-ylamino)methyl)-5-chloro-3-o-tolylpyrrolo[1,2-f][1,2,4]triazin-4(3H)-one 

Relevant academic research and scientific papers

PYRROLOTRIAZINONE DERIVATIVES AS PI3K INHIBITORS

New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).

Pyrrolotriazinone derivatives as PI3K inhibitors

New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks)