1403941-98-9

Upstream product

• 40611-69-6 methyl 3-methyl-1H-pyrrole-2-carboxylate 
• 90724-57-5 3-methyl-1H-pyrrole-2-carboxylic acid 
• 1604801-55-9 2,2,2-trichloro-1-(3-methyl-1H-pyrrol-2-yl)ethanone 
• 616-43-3 3-methylpyrrole 
• 1403941-99-0 3-methyl-N-(o-tolyl)-1H-pyrrole-2-carboxamide 

Downstream Products

• 1403945-83-4 2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylpyrrolo[2,1-f][1,2,4]triazin-4(3H)-one 
• 1604800-72-7 2-((4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-(o-tolyl)pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one 
• 1604801-95-7 2-((4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-(o-tolyl)pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one 
• 1403942-00-6 2-(chloromethyl)-5-methyl-3-(o-tolyl)pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one 

Relevant academic research and scientific papers

PYRROLOTRIAZINONE DERIVATIVES AS PI3K INHIBITORS

New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).

PYRROLOTRIAZINONE DERIVATIVES AS PI3K INHIBITORS

New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).

Pyrrolotriazinone derivatives as PI3K inhibitors

New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks)