1403953-33-2Relevant academic research and scientific papers
Asymmetric synthesis of a highly functionalized enantioenriched system close to thapsigargin framework
Tap, Aurelien,Galvani, Gilles,Sorin, Geoffroy,Lannou, Marie-Isabelle,Ardisson, Janick,Jouanneau, Morgan,Ferezou, Jean-Pierre
, p. 8140 - 8146,7 (2012/12/11)
A straightforward approach to a highly functionalized enantioenriched bicyclo[5.3.0]decadienone system close to the thapsigargin framework has been achieved. The developed synthetic route involves two main stages: installation of the chains on either side of the quaternary center at C7 starting from a central enantiopure epoxide and formation of the bicyclic octahydroazulene through subsequent Pauson-Khand annelation.
