140397-82-6

Usage

Uses

Used in Pharmaceutical Industry:
1H-Pyrazol-5-ol, 3-phenyl-1-(2-pyridinyl)is used as a building block for the synthesis of various biologically active compounds and pharmaceutical drugs. Its unique structure allows for the creation of new molecules with potential therapeutic effects, making it a valuable component in drug discovery and development processes.
Used in Organic Synthesis:
In the field of organic synthesis, 1H-Pyrazol-5-ol, 3-phenyl-1-(2-pyridinyl)serves as a key intermediate for the preparation of complex organic molecules. Its versatile chemical properties enable it to participate in a range of reactions, facilitating the synthesis of diverse organic compounds.
Used as Anti-inflammatory and Analgesic Agent:
1H-Pyrazol-5-ol, 3-phenyl-1-(2-pyridinyl)has shown potential as an anti-inflammatory and analgesic agent, making it a promising candidate for further research and development in the area of pain management and treatment of inflammatory conditions. Its ability to modulate inflammatory responses and alleviate pain positions it as a potential new therapeutic option for various medical conditions.

Upstream product

• 1223597-28-1 2-(5-ethoxy-3-phenyl-1H-pyrazol-1-yl)pyridine 
• 4930-98-7 pyrid-2-ylhydrazine 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 

Downstream Products

• 1198596-04-1 4,4-dibromo-3-phenyl-1-(pyrid-2-yl)-2-pyrazolin-5-one 
• 1396755-34-2 4-hexylidene-3-phenyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol 
• 1357469-76-1 5-chloro-3-phenyl-1-(2-pyridinyl)-1H-pyrazole 
• 1357469-75-0 5-bromo-3-phenyl-1-(2-pyridinyl)-1H-pyrazole 

Relevant academic research and scientific papers

Identification of small molecule inhibitors of human COQ7

Given that the associated clinical manifestations of ubiquinone (UQ, or coenzyme Q) deficiency diseases are highly heterogeneous and complicated, effective new research tools for UQ homeostasis studies are awaited. We set out to develop human COQ7 inhibit

PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR PREVENTING AND TREATING OSTEOPOROSIS CONTAINING SAME

The present invention provides a pyrazole derivative compound and a pharmaceutically acceptable salt thereof. The compound of the invention is remarkably effective for preventing and treating osteoporosis.

COMPOSITION FOR PREVENTING AND TREATING CARDIOVASCULAR DISEASES, CONTAINING PYRAZOLE DERIVATIVE

The present invention provides a composition comprising a pyrazole derivative compound and a pharmaceutically acceptable salt thereof. The composition is remarkably effective for preventing and treating cardiovascular diseases.

PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR PREVENTING AND TREATING OSTEOPOROSIS CONTAINING SAME

The present invention provides a pyrazole derivative compound and a pharmaceutically acceptable salt thereof. The compound of the invention is remarkably effective for preventing and treating osteoporosis.

Dibromination of 5-pyrazolones and 5-hydroxypyrazoles via dibromoisocyanuric acid

(Chemical Equation Presented) A safe and efficient method was developed for the dibromination of pyrazolones and 5-hydroxypyrazoles by use of dibromoisocyanuric acid (DBI). The reaction gave the corresponding dibrominated pyrazolones in excellent yields (≥91%).

Efficient di-bromination of 5-pyrazolones and 5-hydroxypyrazoles by N-bromobenzamide

An efficient and convenient method for the bromination of pyrazolones and 5-hydroxypyrazoles was developed by using N-bromobenzamide in THF at room temperature. This new method provided di-bromimated pyrazolones in excellent yields (≥90%). Crown Copyright