1403989-92-3Relevant academic research and scientific papers
Intramolecular base-free sonogashira reaction for the synthesis of benzannulated chiral macrocycles embedded in carbohydrate templates
Hussain, Altaf,Yousuf, Syed Khalid,Kumar, Deepak,Lambu, Malikharjunarao,Singh, Baldev,Maity, Sudip,Mukherjee, Debaraj
supporting information; experimental part, p. 1933 - 1940 (2012/09/22)
A base-free, intramolecular Sonogashira reaction-based general approach has been established for the diversity-oriented synthesis (DOS) of fused bi- and tricyclic systems containing benzannulated, 10- to 13-membered chiral macrocycles embedded in carbohydrate templates. Macrocycles with different ring sizes have been prepared by pre-designing the chiral building blocks. Base-sensitive groups like acetyl and TBDPS survived the reaction conditions. Copyright
