140405-13-6 Usage
General Description
11-hydroxyyohimbine is a chemical compound derived from yohimbine, which is found in the bark of the yohimbe tree. It is a potent alpha-2 adrenergic receptor antagonist and has been studied for its potential use in the treatment of various medical conditions, including erectile dysfunction and obesity. 11-hydroxyyohimbine has also been investigated for its potential as a treatment for anxiety and depression, as well as for its effects on blood pressure and heart rate. Research has shown that 11-hydroxyyohimbine may have both stimulant and sedative effects, and it is considered to be a promising candidate for further study and development as a pharmaceutical compound. However, it is important to note that 11-hydroxyyohimbine can have side effects and should be used under the guidance of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 140405-13-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,0,4,0 and 5 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 140405-13:
(8*1)+(7*4)+(6*0)+(5*4)+(4*0)+(3*5)+(2*1)+(1*3)=76
76 % 10 = 6
So 140405-13-6 is a valid CAS Registry Number.
InChI:InChI=1/C21H26N2O4/c1-27-21(26)19-15-9-17-20-14(13-4-3-12(24)8-16(13)22-20)6-7-23(17)10-11(15)2-5-18(19)25/h3-4,8,11,15,17-19,22,24-25H,2,5-7,9-10H2,1H3/t11-,15-,17-,18-,19+/m0/s1
140405-13-6Relevant articles and documents
Hydroxylation of yohimbine in superacidic media: One-step access to human metabolites 10 and 11-hydroxyyohimbine
Duflos,Redoules,Fahy,Jacquesy,Jouannetaud
, p. 193 - 195 (2001)
Two major human metabolites of yohimbine (1), 10- and 11-hydroxyyohimbine (2 and 3), were prepared by direct hydroxylation of 1 under superacidic conditions. In this medium, the four positions of the benzene part of yohimbine were hydroxylated and the cor
