140428-71-3

Basic information

• Product Name: Ethanone, 2-chloro-1-(3-methyl-3-phenylcyclobutyl)-
• CAS NO: 140428-71-3
• Molecular Formula: C13H15ClO
• Molecular Weight: 222.715
• Mol File: 140428-71-3.mol

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-chloro-1-(3-methyl-3-phenylcyclobutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-chloro-1-(3-methyl-3-phenylcyclobutyl)-(140428-71-3)
• EPA Substance Registry System: Ethanone, 2-chloro-1-(3-methyl-3-phenylcyclobutyl)-(140428-71-3)

Safety Data

• Hazardous Substances Data: 140428-71-3(Hazardous Substances Data)

Upstream product

• 140428-50-8 1-phenyl-1-methyl-3-(2-chloro-1-hydroxyethyl)cyclobutane 

Downstream Products

• 283604-98-8 4-(1-phenyl-1-methylcyclobutane-3-yl)-2-aminothiazole 
• 1269535-30-9 dimethyl-[(4-{4-{3-methyl-3-phenylcyclobutyl}thiazol-2-yl}hydrazonomethyl)phenyl]amine 
• 646997-58-2 C₂₁H₁₉NO₃ 
• 1607015-94-0 2-(4-allyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-1-(3-methyl-3-phenylcyclobutyl)ethanone 
• 646997-61-7 4-[1-methyl-1-phenylcyclobutane-3-yl]-2-(2-chloroacetamido)thiazole 

Relevant articles and documents

1,1,3-Trisubstituted cyclobutanes containing thiazole and thiourea fragments

The synthesis of 1-aryl-3-(2-chloro-1-hydroxyethyl)-1-methylcyclobutanes, 1-aryl-3-(2-chloro-1-oxoethyl)-1-methylcyclobutanes, 2-amino-4-(3-aryl-3- methylcyclobutyl)thiazoles, and N-[4-(3-aryl-3-methylcyclobutyl)thiazole-2-yl]- N′-arylthioureas is reported. 2006 Springer Science+Business Media, Inc.

Cyclobutane-Substituted Diacetamido Sulfides and 2,5-Diacylthiophenes

A general and convenient route for the synthesis of 2,5-di[1-methyl-1-arylcyclobutane-3-yl]thiophenes 4a-c and bis[1-methyl-1-arylcyclobutane-3-yl]-2-(2-oxoethylamido)thiazole sulfides 7a-c is reported. The characterization of these compounds was obtained by elemental analyses, IR, 13C, and 1H NMR techniques.

FORMATION OF SUBSTITUTED CYCLOBUTANES IN THE REACTION OF 2-(2-METHYL-2-PROPENYL)-3-CHLOROMETHYLOXIRANE WITH AROMATIC HYDROCARBONS

The reaction of 2-(2-methyl-2-propenyl)-3-chloromethyloxiranes with benzene, toluene, and o-, m-, and p-xylenes in the presence of aluminum chloride leads to the formation of 1-aryl-1-methyl-3-(2-chloro-1-hydroxyethyl)cyclobutanes.Dehydrochlorination of t