283604-98-8

Upstream product

• 17356-08-0 thiourea 
• 140428-71-3 1-methyl-1-phenyl-3-(2-chloro-1-oxoethyl)cyclobutane 

Downstream Products

• 646997-61-7 4-[1-methyl-1-phenylcyclobutane-3-yl]-2-(2-chloroacetamido)thiazole 
• 1350565-94-4 [(4-chlorophenyl)({[4-(3-methyl-3-phenylcyclobutyl)-1,3-thiazol-2-yl]amino})methyl]phosphinic acid 
• 1350565-91-1 ({[4-(3-methyl-3-phenylcyclobutyl)-1,3-thiazol-2-yl]amino}(4-nitrophenyl)methyl)phosphinic acid 
• 1350565-93-3 [(4-methoxyphenyl)({[4-(3-methyl-3-phenylcyclobutyl)-1,3-thiazol-2-yl]amino})methyl]phosphinic acid 
• 1350565-90-0 [(2-hydroxynaphthalen-1-yl)({[4-(3-methyl-3-phenylcyclobutyl)-1,3-thiazol-2-yl]amino})methyl]phosphinic acid 

Relevant academic research and scientific papers

1,1,3-Trisubstituted cyclobutanes containing thiazole and thiourea fragments

The synthesis of 1-aryl-3-(2-chloro-1-hydroxyethyl)-1-methylcyclobutanes, 1-aryl-3-(2-chloro-1-oxoethyl)-1-methylcyclobutanes, 2-amino-4-(3-aryl-3- methylcyclobutyl)thiazoles, and N-[4-(3-aryl-3-methylcyclobutyl)thiazole-2-yl]- N′-arylthioureas is reported. 2006 Springer Science+Business Media, Inc.

Cyclobutane-Substituted Diacetamido Sulfides and 2,5-Diacylthiophenes

A general and convenient route for the synthesis of 2,5-di[1-methyl-1-arylcyclobutane-3-yl]thiophenes 4a-c and bis[1-methyl-1-arylcyclobutane-3-yl]-2-(2-oxoethylamido)thiazole sulfides 7a-c is reported. The characterization of these compounds was obtained by elemental analyses, IR, 13C, and 1H NMR techniques.