1404376-40-4Relevant academic research and scientific papers
Intramolecular Schmidt reaction of acyl chlorides with alkyl azides: Rapid access to fused polycyclic nitrogen-containing heterocycles via a multistep one-pot transformation
Gu, Peiming,Kang, Xiao-Yan,Sun, Jian,Wang, Bao-Juan,Yi, Ming,Li, Xue-Qiang,Xue, Ping,Li, Rui
supporting information, p. 5796 - 5799 (2013/01/15)
The first intramolecular Schmidt reaction of acyl chlorides with alkyl azides has been developed. In this one-pot conversion, an ω-azido hydrocinnamic acid is converted to a tricyclic lactam. The most important feature of the process is the efficiency in bond formation (one bond broken and three new bonds created) and ring construction (two new rings formed).
