140438-92-2Relevant academic research and scientific papers
Sigma binding site agents
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, (2008/06/13)
Sigma binding site agents having the formula STR1 which are useful to inhibit sigma binding site-induced activity, pharmaceutical compositions including these agents, and methods of using these agents to inhibit sigma binding site-induced activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented agents.
(Aminoalkoxy)chromones. Selective ? Receptor Ligands
Erickson, Ronald H.,Natalie, Kenneth J.,Bock, William,Lu, Zhijian,Farzin, Farzaneh,et al.
, p. 1526 - 1535 (2007/10/02)
A series of (aminoalkoxy)chromones has been prepared, members of which bind potently (16-100 nM) at the ? binding site and bind weakly (>1000 nm) at the dopamine D2 receptor and 33 other receptors, second messenger systems, and ion channels.At
