6294-17-3

Basic information

• Product Name: 1-Bromo-6-chlorohexane
• Synonyms: HEXAMETHYLENE BROMOCHLORIDE;HEXAMETHYLENE CHLOROBROMIDE;6-BROMOHEXYL CHLORIDE;6-CHLOROHEXYL BROMIDE;1-CHLORO-6-BROMOHEXANE;1-BROMO-6-CHLOROHEXANE;1-Bromo-6-chlorohexa;1-broMo-6-chloroheptane
• CAS NO: 6294-17-3
• Molecular Formula: C₆H₁₂BrCl
• Molecular Weight: 199.52
• EINECS: 228-555-6
• Product Categories: BROMO CHLORO;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;omega-Haloalkyl Chlorides;Alkyl;Halogenated Hydrocarbons;Organic Building Blocks
• Mol File: 6294-17-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 109-110 °C2 mm Hg(lit.)
• Flash Point: 214 °F
• Appearance: /
• Density: 1.337 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.196mmHg at 25°C
• Refractive Index: n20/D 1.481(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 1697304
• CAS DataBase Reference: 1-Bromo-6-chlorohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-6-chlorohexane(6294-17-3)
• EPA Substance Registry System: 1-Bromo-6-chlorohexane(6294-17-3)

Safety Data

• Statements: 36/37/38
• Safety Statements: 23-24/25
• RIDADR: 2810
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 6294-17-3(Hazardous Substances Data)

Usage

Chemical Properties

Clear light yellow liquid

Uses

1-Bromo-6-chlorohexane was used in the synthesis of zinc reagent by reacting with Mg turnings in the presence of ZnCl2 and LiCl.

InChI:InChI=1/C6H12BrCl/c7-5-3-1-2-4-6-8/h1-6H2

Upstream product

• 544-10-5 1-Chlorohexane 
• 629-11-8 1,6-hexanediol 
• 4286-55-9 1-bromo-6-hexanol 
• 2009-83-8 6-chloro-1-hexanol 

Downstream Products

• 24088-97-9 8-chloro-oct-1-yne 
• 172294-02-9 1,2,4,5-Tetrakis-(6-chloro-hexylsulfanylmethyl)-benzene 
• 100649-32-9 (6-chlorohexyl)diphenylphosphane 
• 234090-72-3 2-(6-chlorohexyl)-6-<4-<2-(2-methoxyphenoxy)ethyl>-1-piprazinyl>-3(2H)-pyridazinone 
• 234090-66-5 4-chloro-2-(6-chlorohexyl)-5-<4-<2-(2-methoxyphenoxy)ethyl>-1-piprazinyl>-3(2H)-pyridazinone 
• 71933-93-2 1-chloro-6-phenoxyhexane 
• 875923-68-5 N-[4-(6-chlorohexyloxy)-2-nitrophenyl]acetamide 
• 947604-73-1 p-(6-chlorohexyloxy)bromobenzene 
• 139652-60-1 7-[6-(4-hydroxypiperidinyl)hexoxy]-2-phenyl-4H-1-benzopyran-4-one 
• 544-10-5 1-Chlorohexane 
• 1384457-30-0 C₁₃H₁₉ClSe 
• 1416254-68-6 1-cyclohexylnonan-4-yl 1-naphthoate 
• 135579-83-8 6-chlorohexylzinc bromide 
• 1453475-47-2 C₁₄H₁₇ClO 

Relevant articles and documents

A novel stereoselective one-pot conversion of alcohols into alkyl halides mediated by N,N′-diisopropylcarbodiimide

Alcohols can be converted in high yields to the corresponding alkyl halides in a one-pot procedure via the corresponding O-alkylisourea; very short reaction times are possible when microwave irradiation is used.

Imine-Directed Metalation of o-Tolualdehyde: The Use of Catalytic Amine Base. A Route to 2-(8-Phenyloctyl)benzaldehyde

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8,12-Dialkyl-PGE, and PGF1α

Prostaglandins E1 -type and F1 -type compounds of the formula EQU1 wherein R is hydrogen or a hydrocarbyl group containing from 1 to 12 carbon atoms, inclusive, wherein W is EQU2 or O =, wherein R7, R8, R9, R10, R11, R12, R13, and R14 are hydrogen or alkyl of 1 to 4 carbon atoms, inclusive, provided (1) that at least one of R7, R8, R9, R10, R11, R12, R13, and R14 is alkyl (2) that when R13 is alkyl, at least one of R7, R8, R9, R10, R11, R12, and R14 is alkyl, and (3) that when R7 is alkyl or thwn R7 and R8 are alkyl, at least one of R9, R10, R11, R12, R13, and R14 is alkyl; and the enantiomers and racemic mixtures thereof. These are useful for the same pharmacological purposes as the unsubstituted prostaglandins.