1404432-59-2Relevant academic research and scientific papers
Enantioselective Cross-Exchange between C?I and C?C σ Bonds
Sun, Yu-Li,Wang, Xing-Ben,Sun, Feng-Na,Chen, Qian-Qian,Cao, Jian,Xu, Zheng,Xu, Li-Wen
supporting information, p. 6747 - 6751 (2019/04/26)
A palladium-catalyzed enantioselective intramolecular σ-bond cross-exchange between C?I and C?C bonds is realized, providing chiral indanones bearing an alkyl iodide group and an all-carbon quaternary stereocenter. Pd/TADDOL-derived phosphoramidite is found to be an efficient catalytic system for both C?C bond cleavage and alkyl iodide reductive elimination. In addition to aryl iodides, aryl bromides can also be used for this transformation in the presence of KI. Density-functional theory (DFT) calculation studies support the ring-opening of cyclobutanones occuring through an oxidative addition/reductive elimination process involving PdIV species.
A conjunctive carboiodination: Indenes by a double carbopalladation- reductive elimination domino process
Jia, Xiaodong,Petrone, David A.,Lautens, Mark
supporting information, p. 9870 - 9872 (2012/10/30)
Something gained, nothing lost: A Pd0-catalyzed domino intermolecular/intramolecular process terminated by carbohalogenation is reported. In this reaction, two new C-C bonds, one new C-I bond and one five-membered ring are formed in a single step, and all of the atoms in the starting materials are incorporated into the product (see scheme). Copyright
