140446-91-9

Upstream product

• 4343-75-3 4-amino-2,4-dihydro-[1,2,4]triazole-3-thione 
• 90-02-8 salicylaldehyde 
• 4343-75-3 4-amino-3-mercapto-1,2,4-triazole 

Relevant academic research and scientific papers

Synthesis and biological evaluation of novel hydroxybenzaldehyde-based kojic acid analogues as inhibitors of mushroom tyrosinase

Two series of novel kojic acid analogues (4a–j) and (5a–d) were designed and synthesized, and their mushroom tyrosinase inhibitory activities was evaluated. The result indicated that all the synthesized derivatives exhibited excellent tyrosinase inhibitor

5 - Substituted - 3 - [5 - hydroxy - 4 - pyrone - 2 - yl - methylthio] - 4 - hydroxybenzoic amino - 1, 2, 4 - triazole compound and use thereof

The invention provides novel 5-substituted-3-[5-hydroxyl-4-pyrone-2-yl-methylthio]-4- hydroxybenzyl-methylamino-1,2,4-triazole compounds represented in a formula (I). In the formula (I), a substituent R1 is H, -CH3, -CH2CH3, C6H5-, 2-CH3C6H4-, 3-CH3C6H4-,

Copper complexes with N-aminotriazolethione azomethines: Structures and magnetochemical properties

Azomethine derivatives of 4-amino-1,2,4-triazole-3-thiones (H2L) and their metal complexes were obtained. The stabilities of the ligand conformers were calculated using quantum-chemical techniques. Ab initio (B3LYP/LANL2DZ) calculations of the complexes in the lower singlet and triplet states were performed with full geometry optimization. The structures and magnetochemical properties of the chelate complexes obtained were examined over a wide temperature range.

CONDENSED SYSTEMS BASED ON 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLE

1,2,4-Triazolo-1,3,4-thiadiazines, hydrazones, and β-thio adducts were obtained by reactions of 4-amino-3-mercapto-1,2,4-triazole with ω-bromoacetophenones, aldehydes, and α,β-unsaturated ketones.Conditions that promote the cyclocondensation of the