1404471-59-5

Basic information

• Product Name: 2-bromo-N-[2-(tert-butylamino)-1-(4-chlorophenyl)-2-oxoethyl]-4,5-dimethoxy-N-(prop-2-ynyl)benzamide
• Synonyms: 2-bromo-N-[2-(tert-butylamino)-1-(4-chlorophenyl)-2-oxoethyl]-4,5-dimethoxy-N-(prop-2-ynyl)benzamide
• CAS NO: 1404471-59-5
• Molecular Weight: 521.838
• Mol File: 1404471-59-5.mol

Chemical Properties

• CAS DataBase Reference: 2-bromo-N-[2-(tert-butylamino)-1-(4-chlorophenyl)-2-oxoethyl]-4,5-dimethoxy-N-(prop-2-ynyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N-[2-(tert-butylamino)-1-(4-chlorophenyl)-2-oxoethyl]-4,5-dimethoxy-N-(prop-2-ynyl)benzamide(1404471-59-5)
• EPA Substance Registry System: 2-bromo-N-[2-(tert-butylamino)-1-(4-chlorophenyl)-2-oxoethyl]-4,5-dimethoxy-N-(prop-2-ynyl)benzamide(1404471-59-5)

Safety Data

• Hazardous Substances Data: 1404471-59-5(Hazardous Substances Data)

Upstream product

• 6286-46-0 2-bromo-4,5-dimethoxybenzoic acid 
• 104-88-1 4-chlorobenzaldehyde 
• 2450-71-7 Propargylamine 

Downstream Products

• 1404471-91-5 1-(2-bromo-4,5-dimethoxybenzoyl)-N-(tert-butyl)-2-(4-chlorophenyl)-2,3-dihydro-1H-pyrrole-2-carboxamide 

Relevant articles and documents

Two-step synthesis of 2,3-dihydropyrroles via a formal 5-endo cycloisomerization of Ugi 4-CR/propargyl adducts

A practical two-step synthesis of 2,3-dihydropyrroles from Ugi 4-CR/propargyl adducts is presented. The protocol includes a base-mediated formation of an allenamide functional group and an in situ metal-free formal 5-endo cycloisomerization that occurs in a highly regioselective manner at the allenamide C-γ.