1404473-96-6

Basic information

• Product Name: (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-1-oxopropan-2-yl 3-(phosphonooxy)benzoate
• Synonyms: (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-1-oxopropan-2-yl 3-(phosphonooxy)benzoate
• CAS NO: 1404473-96-6
• Molecular Weight: 749.536
• Mol File: 1404473-96-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-1-oxopropan-2-yl 3-(phosphonooxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-1-oxopropan-2-yl 3-(phosphonooxy)benzoate(1404473-96-6)
• EPA Substance Registry System: (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-1-oxopropan-2-yl 3-(phosphonooxy)benzoate(1404473-96-6)

Safety Data

• Hazardous Substances Data: 1404473-96-6(Hazardous Substances Data)

Upstream product

• 958025-66-6 MPC-3100 
• 1404475-90-6 C₃₃H₃₈BrN₆O₉PS 
• 805967-04-8 3-diethoxyphosphoryloxybenzoic acid 
• 1156468-60-8 tert-butyl 4-{2-[6-amino-8-(1,3-benzodioxol-5-ylthio)-9H-purin-9-yl]ethyl}piperidine-1-carboxylate 
• 1156468-58-4 tert-butyl 4-[2-(6-amino-8-bromo-9H-purin-9-yl)ethyl]piperidine-1-carboxylate 
• 1156468-55-1 tert-butyl 4-[2-(6-amino-9H-purin-9-yl)ethyl]piperidine-1-carboxylate 
• 169457-73-2 tert-butyl 4-(2-bromoethyl)piperidine-1-carboxylate 
• 66224-66-6 adenine 
• 99-06-9 3-Carboxyphenol 

Relevant articles and documents

Discovery of an l-alanine ester prodrug of the Hsp90 inhibitor, MPC-3100

Various types of Hsp90 inhibitors have been and continue to undergo clinical investigation. One development candidate is the purine-based, synthetic Hsp90 inhibitor 1 (MPC-3100), which successfully completed a phase I clinical study. However, further clin