1404480-15-4

Basic information

• Product Name: 2-amino-benzooxazole-5-boronic acid hydrochloride
• Synonyms: 2-amino-benzooxazole-5-boronic acid hydrochloride
• CAS NO: 1404480-15-4
• Molecular Weight: 214.416
• Mol File: 1404480-15-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-amino-benzooxazole-5-boronic acid hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-benzooxazole-5-boronic acid hydrochloride(1404480-15-4)
• EPA Substance Registry System: 2-amino-benzooxazole-5-boronic acid hydrochloride(1404480-15-4)

Safety Data

• Hazardous Substances Data: 1404480-15-4(Hazardous Substances Data)

Usage

Chemical compound

2-amino-benzooxazole-5-boronic acid hydrochloride

Structure

Contains a benzooxazole ring with an amino group and a boronic acid group attached to it.

Form

Hydrochloride salt

Usage

Commonly used in organic chemistry as a reagent for synthesizing various organic molecules.

Boronic Acid Group

Makes it valuable for synthesizing complex organic molecules, facilitating the formation of carbon-carbon and carbon-heteroatom bonds.

Stability

The hydrochloride salt form enhances stability and ease of handling in laboratory settings.

Upstream product

• 1224844-66-9 5-( 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2-amine 
• 40925-68-6 2-amino-4-bromo-phenol 
• 64037-07-6 5-bromo-1,3-benzoxazol-2-amine 
• 73183-34-3 bis(pinacol)diborane 
• 106-41-2 4-bromo-phenol 
• 7693-52-9 4-bromo-2-nitrophenol 
• 1404480-03-0 C₇H₇BrN₂OS 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 1268454-23-4 (6-(2-aminobenzo[d]oxazol-5-yl)imidazo[1,2-a]pyridin-3-yl)(morpholino)methanone 
• 1224844-38-5 INK128 

Relevant articles and documents

Pyrazole compound and preparation and application methods thereof

The invention provides a pyrazole compound and preparation and application methods thereof. The pyrazole compound is synthesized by introducing 2-amido-benzoxazole groups into pyrazole. The prepared pyrazole compound is low in toxic and side effects, high in oral bioavailability, significant in inhibition on tumor cells such as human breast cancer cells, human lung cancer cells, human prostatic cancer cells, human gastric cancer cells and human malignant glioma cells and capable of providing new possibilities for developing high-efficiency and low-toxicity anti-tumor drugs. Meanwhile, the pyrazole compound is wide in material sources, simple in synthesizing processes and applicable to industrial production.

(1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide for use in treating HCV

The invention relates to an administration unit comprising a compound of formula and/or pharmaceutically acceptable salts thereof, and to a packaging comprising the administration unit according to the invention.

COMBINATION OF KINASE INHIBITORS AND USES THEREOF

The present invention provides for a method for treating a disease condition associated with PI3-kinase a and/or mTOR in a subject. In another aspect, the invention provides for a method for treating a disease condition associated with PI3-kinase a and/or mTOR in a subject. In yet another aspect, a method of inhibiting phosphorylation of both Akt (S473) and Akt (T308) in a cell is set forth. The present invention also provides a pharmaceutical kit effective for treating a disease condition associated with PI3 -kinase α and/or mTOR in a subject.