140477-48-1Relevant academic research and scientific papers
N -Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N -sulfonyl amidines
Yang, Weiguang,Huang, Dayun,Zeng, Xiaobao,Luo, Dongping,Wang, Xinyan,Hu, Yuefei
supporting information, p. 8222 - 8225 (2018/07/29)
A highly reactive intermediate N-sulfonyl acetylketenimine was generated from a 3-butyn-2-one participating CuAAC/ring-opening method. Its high reactivity due to bearing two EWGs allowed us to offer the first example of a reaction between ketenimine and amide to synthesize N-sulfonyl amidines efficiently.
Mild reductive functionalization of amides into N-sulfonylformamidines
Trillo, Paz,Slagbrand, Tove,Tinnis, Fredrik,Adolfsson, Hans
, p. 484 - 487 (2018/08/17)
The development of a protocol for the reductive functionalization of amides into N-sulfonylformamidines is reported. The one-pot procedure is based on a mild catalytic reduction of tertiary amides into the corresponding enamines by the use of Mo(CO)6 (molybdenum hexacarbonyl) and TMDS (1,1,3,3-tetramethyldisiloxane). The formed enamines were allowed to react with sulfonyl azides to give the target compounds in moderate to good yields.
TRICHLOROMETHYL GROUP AS A NUCLEOFUGE IN THE REACTION OF AZOMETHINES WITH AMINES
Krasnov, V.L.,Vasyanina, G.I.,Bodrikov, I.V.
, p. 1359 - 1362 (2007/10/02)
In the reaction of N-(2,2,2-trichloroethylidene)-4-R-benzoylsulfonamides (R = H, Cl, CH3) with aliphatic secondary amines N,N-dialkyl-N'-arylsulfonylformamidines are formed as substitution products of the trichloromethyl group.Thus, the trichloromethyl gr
