14052-59-6

Basic information

• Product Name: Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylthio)phenyl]eth yl]-
• CAS NO: 14052-59-6
• Molecular Formula: C12H15Cl2NO3S
• Molecular Weight: 324.228
• Mol File: 14052-59-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylthio)phenyl]eth yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylthio)phenyl]eth yl]-(14052-59-6)
• EPA Substance Registry System: Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylthio)phenyl]eth yl]-(14052-59-6)

Safety Data

• Hazardous Substances Data: 14052-59-6(Hazardous Substances Data)

Upstream product

• 1768-31-6 pentachloroacetone 
• 14172-52-2 (1RS,2RS)-2-amino-1-(4-methylsulfanyl-phenyl)-propane-1,3-diol 
• 872302-03-9 dichloroacetyl-phosphorous acid diethyl ester 
• 119293-92-4 (+/-)-2-dichloroacetamido-β-hydroxy-4-methylmercaptopropiophenone 
• 535-15-9 ethyl 1,1-dichloroacetate 
• 23150-33-6 (1RS,2RS)-2-acetylamino-1-(4-methylsulfanyl-phenyl)-propane-1,3-diol 

Downstream Products

• 7780-07-6 (+/-)-threo and (+/-)-erythro-1-p-methanosulfonylphenyl-2-dichloroacetamido-1,3-propanediol 
• 16854-32-3 (1S,2S)-(+)-thiomicamine 
• 23150-35-8 (R*,R*)-(+)-thiomicamine 
• 27348-48-7 (+)-(1S,2R)-2-amino-1-<4-(methylthio)phenyl>-1,3-propanediol 
• 51458-28-7 (1R,2R)-2-amino-1-<4-(methylsulphonyl)phenyl>-1,3-propanediol 
• 51591-89-0 (1S,2S)-2-amino-1-(4-(methylsulfonyl)phenyl)propane-1,3-diol 
• 847-25-6 (+/-)-Thiamphenicol 

Relevant articles and documents

Process of preparing thiamphenicol

Process of preparing thiamphenicol represented by formula [II] below which comprises:, a step of diazotizing the aromatic amino group of the compound represented by formula [I] below;, a step of subsequently reacting a methylthio metal salt with said diazonium compound to convert the amino group into a methylthio group; and, a combination of a step of dichloroacetylating the aliphatic amino group and a step of oxidizing the methylthio group.