140630-40-6Relevant academic research and scientific papers
Enzyme Assisted Preparation of Enantiomerically Pure β-Adrenergic Blockers II. Building Blocks of High Optical Purity and their Synthetic Conversion
Ader, Ulrich,Schneider, Manfred P.
, p. 205 - 208 (2007/10/02)
Based on previous screening results a series of potential building blocks 2-4 for β-adrenergic blockers were prepared both by enzymatic hydrolysis and acyltransfer and further transformed into the corresponding oxiranes and aminoalcohols of defined absolu
A Simplified Procedure for the Stereospecific Transformation of 1,2-Diols into Epoxides
Kolb, Hartmuth C.,Sharpless, K. Barry
, p. 10515 - 10530 (2007/10/02)
A simple, 'one-pot' procedure for the conversion of vicinal diols into epoxides via halohydrin ester intermediates has been developed.This method tolerates a wide range of functionality including acid sensitive functional groups.The transformation proceed
