140650-90-4Relevant articles and documents
SYNTHESIS AND SOME PROPERTIES OF ETHYL 2-OXO-4-CYANO-1-OXASPIRODECANE-3-CARBOXYLATE
Kuroyan, R. A.,Pogosyan, S. A.,Grigoryan, N. P.
, p. 821 - 823 (2007/10/02)
It was established by NMR and mass spectrometry that 1-oxaspirooctane-2-carboxylic acid nitrile is converted, by the action of sodium malonate in toluene, to ethyl 2-oxo-4-cyano-1-oxaspirodecane-3-carboxylate, which, upon refluxing in DMSO, is de-ethoxycarbonylated to give 2-oxo-1-oxaspirodecane-4-carboxylic acid nitrile.The latter is converted to a thioamide, on the basis of which some thiazoles were synthesized.