36929-66-5

Basic information

• Product Name: 1-OXASPIRO[2.5]OCTANE-2-CARBONITRILE
• Synonyms: 1-Oxaspiro[2.5]octane-2-carbonitrile(6CI,9CI)
• CAS NO: 36929-66-5
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.18
• Product Categories: EPOXYDE;Ring Systems
• Mol File: 36929-66-5.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-OXASPIRO[2.5]OCTANE-2-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-OXASPIRO[2.5]OCTANE-2-CARBONITRILE(36929-66-5)
• EPA Substance Registry System: 1-OXASPIRO[2.5]OCTANE-2-CARBONITRILE(36929-66-5)

Safety Data

• Hazardous Substances Data: 36929-66-5(Hazardous Substances Data)

Usage

General Description

1-Oxaspiro[2.5]octane-2-carbonitrile is a chemical compound, often referred to by its systematic name, which contains a spiro ring structure, meaning two rings share one single atom. This unique structure can be found in many naturally occurring and synthetic compounds, including pharmaceuticals and agrochemicals. Its molecular formula is C8H11NO, suggesting that it is composed of carbon, hydrogen, nitrogen, and oxygen atoms. 1-Oxaspiro[2.5]octane-2-carbonitrile may be used in a variety of applications in the fields of chemistry and pharmacology. However, information about the compound's physical properties or safety measures is not widely available, suggesting that it might not be a well-studied or commonly used substance.

Upstream product

• 108-94-1 cyclohexanone 
• 107-14-2 chloroacetonitrile 

Downstream Products

• 117169-30-9 1-Fluoro-1-hydroxymethylcyclohexane 
• 117169-31-0 1-Fluorocyclohexanecarboxylic acid 
• 117169-32-1 Methyl 1-fluorocyclohexanecarboxylate 
• 117169-33-2 dimethyl [2-(1-fluorocyclohexyl)-2-oxoethyl]phosphonate 
• 117169-34-3 C₂₄H₃₇FO₅ 
• 117189-39-6 5,5-(1,2-Ethanediyldioxy)-1-exo-<3-(1-fluorocyclohexyl)-3-oxo-(E)-1-propenyl>-2-endo-(tetrahydropyran-2-yloxy)octahydropentalene 
• 117169-35-4 1-exo-<3-(1-Fluorocyclohexyl)-3(S)-hydroxy-(E)-1-propenyl>-2-endo-hydroxy-5-oxooctahydropentalene 
• 117169-35-4 1-exo-<3-(1-Fluorocyclohexyl)-3(R)-hydroxy-(E)-1-propenyl>-2-endo-hydroxy-5-oxooctahydropentalene 
• 117169-36-5 <(5E,Z),(13E)>-15-(1-Fluorocyclohexyl)-11α,(15S)-dihydroxy-ω-pentanor-9a-carbaprostacyclin 
• 117169-36-5 <(5E,Z),(13E)>-15-(1-Fluorocyclohexyl)-11α,(15R)-dihydroxy-ω-pentanor-9a-carbaprostacyclin 
• 140650-90-4 4-[4-(4-Nitro-phenyl)-thiazol-2-yl]-1-oxa-spiro[4.5]decan-2-one 
• 140650-89-1 4-[4-(4-Chloro-phenyl)-thiazol-2-yl]-1-oxa-spiro[4.5]decan-2-one 
• 140650-88-0 4-(4-Phenyl-thiazol-2-yl)-1-oxa-spiro[4.5]decan-2-one 
• 79205-63-3 (fluoro-1 cyclohexyl) glycolle 

Relevant articles and documents

ALPHA-HYDROXY-BETA-AZIDO-TETRAZOLES

Alpha-hydroxy-beta-azido tetrazole compounds of formula (I): a process for manufacturing alpha-hydroxy-beta-azido tetrazoles of formula (I), and their use for synthesizing new compounds, e.g. in “click” chemistry.

Quaternary ammonium salts used as phase transfer catalyst

Novel quaternary ammonium salts of general formula (I) STR1 wherein: R is a saturated or unsaturated, linear or branched alkyl radical of C1 to C8. R' is a saturated or unsaturated, linear or branched alkyl radical of C1 to C12, or a benzyl radical. n is a number equal to 2 or 3. Xθ is a halogenide anion, such as Clθ, Brθ, Iθ, are used as phase transfer catalysts, in heterogeneous ionic reactions wherein the reagents are in different phase and have different polarity.

NEW SYNTHETIC ROUTES TO β-FLUORO β-PHENYLLACTIC ACID DERIVATIVES AND Β-FLUOROCYANOHYDRINS

Alkyl phenyl 2,3-epoxycarboxylates from the well-known Darzens glycidic esters synthesis react under very mild conditions with pyridinium-poly-hydrogen fluoride to give corresponding 3-fluoro 3-phenyllactates in almost quantitative yields with a high regio and stereoselectivity.This method can be applied succesfully to other flycidic derivatives: glycidoamides, glycidonitriles, glycidoiminoesters...The spectrometric properties (IR, NMR) are presented.