140667-09-0

Basic information

• Product Name: 2-Pyrrolidinone, 4-methyl-3-[(phenylthio)methyl]-1-(2-propenyl)-, trans-
• CAS NO: 140667-09-0
• Molecular Formula: C15H19NOS
• Molecular Weight: 261.388
• Mol File: 140667-09-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Pyrrolidinone, 4-methyl-3-[(phenylthio)methyl]-1-(2-propenyl)-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinone, 4-methyl-3-[(phenylthio)methyl]-1-(2-propenyl)-, trans-(140667-09-0)
• EPA Substance Registry System: 2-Pyrrolidinone, 4-methyl-3-[(phenylthio)methyl]-1-(2-propenyl)-, trans-(140667-09-0)

Safety Data

• Hazardous Substances Data: 140667-09-0(Hazardous Substances Data)

Upstream product

• 3085-68-5 N,N-diallylacrylamide 
• 108-98-5 thiophenol 
• 882-33-7 diphenyldisulfane 
• 124-02-7 diallylamine 

Relevant articles and documents

Radical Cyclisation in Heterocycle Synthesis. Part 1. Sulfanyl Radical Addition-Cyclisation of Dienylamides for Lactam Synthesis

A new method for the synthesis of five- to eight-membered lactams by sulfanyl radical mediated-cyclisation of dienylamides is described.The sulfanyl radical addition-cyclisation of the dienylamide 1 was systematically investigated under four different conditions and was found to give the cyclised lactams 2-6 in 54-79percent yield.The stereo- and regio-selectivity of sulfanyl radical addition-cyclisation was established from the preferential formation of the trans-cyclised lactam 3 and also from the substituent effects in the cyclisation of the dienylamides 11-18.The sulfanyl radical mediated addition-cyclisation was successfully applied to the construction of the six- and eight-membered lactams 28a, b.